The scope of this study is to investigate the effect of different exercise programs on cognitive functions and functionality of persons suffering from mild Alzheimer’s disease (AD) by generating information on the exercise types and their parameters. But it is necessary to update the CNAD and conduct a study with a bigger sample.ĭementia causes deterioration in cognitive and physical functions. The CNAD has evaluation value and screening value for patients with cognitive impairment and SACAS. In analysis of ROC curve, the Stroop color-word test (p = 0.002), one back test (p = 0.013), and identification test (p = 0.006), and comprehensive index of the three tests (p = 0.001) had the diagnostic value. The analysis of linear regression equation indicated that cognitive scores of stenosis patients declined faster with age, especially for digit span test, Stroop color-word test, one back test and identification test. Stenosis patients had worse scores for Stroop color-word test (p = 0.002), one back test (p = 0.013), and identification test (p = 0.006) corresponding to attention and executive ability. Stenosis and control subjects had no statistically significant differences in baseline characteristics. The diagnostic value of CNAD was evaluated by the receiver operating characteristic (ROC) curve. The relationship of scores of cognitive tests and age were analyzed in the linear regression equation. The differences of cognitive function were analyzed between patients and controls. Duplex ultrasound defined the degree of stenosis. There were 48 patients with ≥70% asymptomatic carotid stenosis and 52 controls without carotid stenosis. The diagnostic value of screening SACAS of the CNAD was analyzed. This study aimed to evaluate the impact of severe asymptomatic carotid artery stenosis (SACAS) on cognitive function by a computerized neuropsychological assessment device (CNAD). Moreover, the cognitive function was assessed mostly by paper and pencil cognitive tests. Carotid stenosis can lead to stroke and cognitive impairment.
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